:3002 · live

ClinKernel

Adverse event capture, clinical trial state machines, SUSAR reporting, CAPA cycles, SOP lifecycle management — all on the same kernel as procurement.

Open admin →API reference Architecture

Autonomous capabilities

01

GxP electronic records (21 CFR Part 11 ready)

02

Adverse event ingestion + SUSAR escalation

03

Clinical trial state machine (10 transitions)

04

CAPA cycle automation

05

SOP lifecycle versioning

06

Document state machine (8 transitions)

Live event stream

Real-time tail of the kernel event bus for this vertical. Hash-chained, immutable, public via Evidence API.

events.live · life-sciencestail -f

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Agent handoff

Stateless edge functions. Coordination via the database event bus, not RPC.

01ae-intake

02triage-agent

03assessment-agent

04susar-escalator

05capa-agent

Use cases

Where this lands

SUSAR auto-escalation

AE intake → MedDRA classification → severity/expectedness → 7-day clock for serious unexpected. EMA + FDA pathways auto-routed.

7d avg response

Trial state-machine governance

Every trial state transition (design→enrolling→active→locked→closed) requires evidence and signature. No silent edits.

21 CFR Part 11

Document lifecycle

Single-current-version invariant. Every superseded SOP retained immutably. Effective dating built in.

0 stale-SOP incidents

CAPA cycles

Root cause → action → verification → close. Each stage gated by evidence. CAPA register exportable for inspection.

< 30d median CAPA

Under the hood

How it maps to the kernel

Same Postgres-source-of-truth, same hash-chained audit, same agent runtime — sliced by aggregate. Each vertical is a config of tables + agents + /v1/* endpoints, not a fork of the kernel.

Database tables

▸ ontology_object_types
▸ tenant_object_types
▸ compliance_assessments
▸ compliance_findings
▸ audit_events

Agents wired

▸ orchestrator
▸ supplier-kyc

/v1/* endpoints

▸ GET /v1/ontology/object-types
▸ POST /v1/tenant/ontology/object-types
▸ POST /v1/compliance/assess
▸ GET /v1/audit/verify

Try it

Open the live admin

The same kernel that runs in this preview is the kernel you self-host. Every link below is wired to a real route — the data is seeded, the agents respond, and the audit chain is verifiable.